Extracellular tumor-related mRNA in plasma of lymphoma patients and survival implications.
BACKGROUND: We studied anomalous extracellular mRNAs in plasma from patients with diffuse large B-cell lymphoma (DLBCL) and their survival implications.mRNAs studied have been reported in the literature as markers of poor (BCL2, CCND2, MYC) and favorable outcome (LMO2, BCL6, FN1) in tumors.These markers were also analyzed in lymphoma tissues to tes